Calprotectin

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Fecal Calprotectin Testing

There are two main forms of the disorder, Crohn’s disease (CD) and ulcerative colitis (UC). Noninvasive diagnosis of inflammatory intestinal disease is difficult because the clinical manifestation of intestinal disorders and colon cancer are relatively non-specific. For example, a patient presenting with diarrhea or abdominal pain has a wide range of diagnostic possibilities. Endoscopy with his...

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Fecal Calprotectin Testing

INSTRUCTIONS FOR USE This Medical Policy provides assistance in interpreting UnitedHealthcare benefit plans. When deciding coverage, the enrollee specific document must be referenced. The terms of an enrollee's document (e.g., Certificate of Coverage (COC) or Summary Plan Description (SPD) and Medicaid State Contracts) may differ greatly from the standard benefit plans upon which this Medical P...

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Calprotectin in Cystic Fibrosis

BACKGROUND There is increasing evidence that intestinal inflammation plays a major role in gastrointestinal symptoms in cystic fibrosis (CF). Fecal calprotectin is a marker that is elevated in several gastrointestinal inflammatory diseases, but little is known about its value in CF. We aimed to look for associations of elevated fecal calprotectin among CF patients and whether its level correlat...

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[Measurement of calprotectin in faeces].

BACKGROUND Calprotectin is a calcium-binding protein found in neutrophils. Increased levels are found in stools after mucosal damage due to inflammation, which causes influx of neutrophils into the gut lumen. MATERIAL AND METHOD This article is based on a review of the most pertinent publications found on Medline and our clinical experience from more than 10 years of using the test. RESULTS...

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Calprotectin (S100A8/A9) in Familial Mediterranean Fever

Introduction Calprotectin (S100A8/A9) is an example of a damage associated molecular pattern and a TLR4 ligand. It is expressed in neutrophils, monocytes and early infiltrating macrophages. Calprotectin, once secreted, has a number of proinflammatory effects on activated endothelium and on phagocytes and reflects activation of the innate immune system. Calprotectin has been demonstrated to be s...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 2007

ISSN: 0003-4932

DOI: 10.1097/sla.0b013e3180f61af4